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Some people have inherited faulty genes that increase their risk of developing particular types of cancer. The link between the BRCA1 gene and breast cancer was discovered in the 1990s using early genome sequencing techniques. Fast-forward to the present day and researchers at the Oxford Genomics Centre are working at the cutting edge of disease prevention and treatment using new faster and more efficient methods of sequencing.

This activity is suitable for extending the more able and asks students to take the role of a genetic counsellor advising someone who has the faulty BRAC1 gene and therefore an increased risk of developing breast and ovarian cancer.

Learning Outcomes:

  • Students learn how a mutation can increase the risk of developing cancer
  • Students interpret information in order to advise a person in the role of a genetic counsellor

See more at: www.oxfordsparks.ox.ac.uk/content/how-read-dna

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