Principles of HOMEOSTASIS and NEGATIVE FEEDBACK (AQA A-level Biology)

This is a fully-resourced lesson which has been designed to cover specification point 6.4.1 of the AQA A-level Biology specification. The resource contains a detailed and engaging PowerPoint and accompanying worksheets which ensure that students can apply their understanding of the principles of homeostasis to include the regulation by negative feedback.

As homeostasis is a topic met at GCSE, this lesson has been written to build on this knowledge as well as to check on their prior knowledge of earlier A-level topics such as osmosis when considering blood water potential and the use of glucose as a respiratory substrate. Discussion points are written into the lesson at regular intervals to encourage the students to consider why a particular process or method takes place and understanding checks allow them to assess their progress. Students will recall how body temperature, blood water potential and blood glucose concentration are maintained within restricted limits and the importance of these systems are looked into in detail. Time is taken to consider the importance of maintaining these aspects, specifically with relation to the activity of enzymes. As such, students will also discuss how the pH of the blood is maintained. The key components of the control system are recalled and then time is taken to focus on the cell signalling that occurs between the coordination centre and the effectors. Students will learn to associate the response with either the use of the neuronal or hormonal system. The final part of the lesson looks at the importance of negative feedback in reversing the change in order to bring the aspect back to the optimum and the added degree of control which this provides. Positive feedback is also briefly mentioned at the end.

This lesson has been written for A-level students who are studying the AQA A-level Biology course and because of the detail of this specification point, it is likely that this resource will cover 2 or more lessons in order for deep understanding to be developed.

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  • Principles-of-homeostasis-and-negative-feedback.pptx
  • Newspaper-about-homeostasis.docx
  • The-autonomic-control-of-heart-rate.docx
  • Regulating-metabolic-rate.docx

About this resource


Created: Sep 17, 2019

Updated: Oct 16, 2019

Whole lesson

pptx, 1 MB



docx, 238 KB



docx, 14 KB


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