Three charities, including the Esmee Fairbairn foundation, one of the largest independent grand-making foundations in the UK, have given a pound;9,000 grant to Bethnal Green primary in Hackney for the scheme.
Dr Lorna Robinson, a classics teacher from Oxford, will travel to the school three times a week to teach the pupils, who come from a wide range of ethnic backgrounds.
She hopes to hold a conference later this year to present her findings on the pilot and explore its impact on literacy.
Dr Robinson previously set up the Iris Project, a scheme to increase the teaching of Latin in comprehensive schools. She said: "I believe Latin is providing a wonderful new aspect to these children's school curriculum and that they are being given a fantastic tool which will help them in the future with their English, history, and other disciplines."