AQA new specification-Making monoclonal antibodies-B6.5

Making monoclonal antibodies lesson created in accordance to the NEW AQA Specification (9-1). Designed for a higher ability SEPARATE (trilogy) class, although content can be adjusted to suit any ability. Includes: slide animations, embedded videos and practice questions with answers on slides.

NB: This resource is for separate science only

AQA spec link:
Relevant chapter: B6 Preventing and treating diseases. AQA Biology third edition textbook-Page 106-107

Specification requires students to know the following;

Students should be able to describe how monoclonal antibodies are produced.
Monoclonal antibodies are produced from a single clone of cells. The antibodies are specific to one binding site on one protein antigen and so are able to target a specific chemical or specific cells in the body.
They are produced by stimulating mouse lymphocytes to make a particular antibody. The lymphocytes are combined with a particular kind of tumour cell to make a cell called a hybridoma cell. The hybridoma cell can both divide and make the antibody. Single hybridoma cells are cloned to produce many identical cells that all produce the same antibody. A large amount of the antibody can be collected and purified.

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  • B6.5-Making-monoclonal-Ab.pptx

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Created: Sep 7, 2019

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