This lesson describes the sequence of events that occur during the phagocytosis of pathogens and the subsequent destruction by lysozymes. The engaging and detailed PowerPoint and accompanying resources have been primarily designed to cover the second part of point 2.4 of the AQA A-level Biology specification but includes an introduction to antigen-presentation so that the students are prepared for upcoming lessons on the cellular and humoral responses. At the start of the lesson, the students are challenged to recall that cytosis is a suffix associated with transport mechanisms and this introduces phagocytosis as a form of endocytosis which takes in pathogens and foreign particles. This emphasis on key terminology runs throughout the course of the lesson and students are encouraged to consider how the start or end of a word can be used to determine meaning. The process of phagocytosis is then split into 5 key steps and time is taken to discuss the role of opsonins as well as the fusion of lysosomes and the release of lysozymes. A series of application questions are used to challenge the students on their ability to make links to related topics including an understanding of how the hydrolysis of the peptidoglycan wall of a bacteria results in lysis. Students will be able to distinguish between neutrophils and monocytes from a diagram and at this point, the role of macrophages and dendritic cells as antigen-presenting cells is described so that it can be used in the next lesson. The lesson concludes with a brief introduction to lymphocytes so that initial links between phagocytosis and the specific immune responses are made.

This engaging lesson uses the example of resistant bacteria and the modern-day giraffe to describe how natural selection occurs. The PowerPoint and accompanying resources have been designed to cover point 17.2 (a) of the CIE A-level Biology specification but also explains that genetic diversity is important for selection and therefore covers 17.1 (d) at the same time. President Trump’s error ridden speech about viruses antibiotics is used at the beginning of the lesson to remind students antibiotics are actually a treatment for bacterial infections. Moving forwards, 2 quick quiz competitions will initially introduce MRSA and then will show the students that they can use this abbreviation to remind them to use mutation, reproduce, selection (and survive) and allele in their descriptions of evolution through natural selection. The main task of the lesson challenges the students to form a description that explains how this strain of bacteria developed resistance to methicillin. In doing so, they will see the principles of natural selection so they can be applied to different situations such as describing how the anatomy of the modern-day giraffe has evolved over time. The final part of the lesson introduces adaptations and convergent evolution and also links to the need for modern classification techniques which is covered later in topic 17.

This detailed lesson describes the relationship between the structure, properties and roles of water for living organisms. The engaging PowerPoint and accompanying resource have been designed to cover the details of specification point 2.1.2 (a) of the OCR A-level Biology A course and has been specifically designed to ensure that each role is illustrated using an example in prokaryotes or eukaryotes. As this is the first lesson in the biological molecules sub-module (2.1.2), which is a topic that students tend to find difficult or potentially less engaging, the planning has centred around the inclusion of a wide variety of tasks to cover the content whilst maintaining motivation and engagement. These tasks include current understanding and prior knowledge checks, discussion points and quick quiz competitions to introduce key terms and values in a memorable way. The start of the lesson considers the structure of water molecules, focusing on the covalent and hydrogen bonds, and the dipole nature of this molecule. Time is taken to emphasise the importance of these bonds and this property for the numerous roles of water and then over the remainder of the lesson, the following properties are described and discussed and linked to real-life examples: As a solvent to act as a transport medium in blood plasma Molecules are attracted by cohesive forces to enable transport in the xylem High latent heat of vaporisation for thermoregulation High specific heat capacity for the maintenance of a stable environment Peak density in the liquid form allowing ice to float The final part of the lesson introduces condensation and hydrolysis reactions and students will learn that a clear understanding of these reactions is fundamental as they will reappear throughout the module in the synthesis and breakdown of biological molecules.

This lesson describes the mechanisms of ventilation and gas exchange in insects. The PowerPoint and accompanying worksheets are the part of the second lesson in a series of 2 lessons which have been designed to cover the details that are set out in point 3.1.1 (f) of the OCR A-level Biology A specification. The first lesson in this series describes ventilation and gas exchange in bony fish In the previous lesson, the students were introduced to the different circulatory systems of mammals and bony fish and this knowledge is checked upon at the start of this lesson. This is relevant because the open circulatory system of an insect explains how oxygen is not transported in the blood but instead is absorbed from the body fluid that bathes the tissues. The next part of the lesson describes the structure of the spiracles, tracheae and tracheoles in the tracheal system and explains how this system is responsible for the delivery of oxygen to the open end of the tracheole for gas exchange with this fluid. As the tracheae are supported by chitin, which is similar in structure and function to cellulose and keratin respectively, a series of exam-style questions are used to challenge the students on their knowledge of those polymers from module 2.1.2 (biological molecules). As always, the mark scheme is embedded in the powerpoint so students can assess their understanding and progress. The final part of the lesson describes how squeezing of the tracheoles by the flight muscles and the changes in the volume of the thorax as a result of the movement of the wings are similar to mechanisms observed in mammals.

This detailed lesson describes the structure of a nucleotide and a phosphorylated nucleotide and explains how polynucleotides are synthesised and broken down. The engaging PowerPoint has been designed to cover points [a], [b] and [c] of module 2.1.3 as detailed in the OCR A-level Biology A specification and links are made throughout to earlier topics such as biological molecules. Students were introduced to the term monomer and nucleotide in the previous module, so the start of the lesson challenges them to recognise this latter term when only the letters U, C and T are shown. This has been designed to initiate conversations about why only these letters were used so that the nitrogenous bases can be discussed later in greater detail. Moving forwards, students will learn that a nucleotide is the monomer to a polynucleotide and that deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are two examples of this type of polymer. The main part of the lesson has been filled with various tasks that explore the structural similarities and structural differences between DNA and RNA. This begins by describing the structure of a nucleotide as a phosphate group, a pentose sugar and a nitrogenous base. Time is taken to consider the details of each of these three components which includes the role of the phosphate group in the formation of a phosphodiester bond between adjacent nucleotides on the strand. At this point students are challenged on their understanding of condensation reactions and have to identify how the hydroxyl group associated with carbon 3 is involved along with the hydroxyl group of the phosphoric acid molecule. A number of quiz rounds are used during this lesson, as a way to introduce key terms in a fun and memorable way. One of these rounds introduces adenine and guanine as the purine bases and thymine, cytosine and uracil as the pyrimidine bases and the students are shown that their differing ring structures can be used to distinguish between them. The remainder of the lesson focuses on ADP and ATP as phosphorylated nucleotides and links are made to the hydrolysis of this molecule for energy driven reactions in cells such as active transport

This is a fully-resourced revision lesson which covers the content detailed in topic 10 (electricity and circuits) of the Pearson Edexcel GCSE Physics specification. The engaging PowerPoint and accompanying resources contain a wide range of activities which include exam-style questions with clearly explained answers, differentiated tasks and quiz competitions to allow students to assess their understanding and ultimately recognise those areas which need further consideration. The following specification points have been given particular attention in this lesson: The electrical symbols that represent the electrical components Describe the differences between series and parallel circuits Recall that a voltmeter is connected in parallel One volt is equal to one joule per coulomb Recall and use the equations that calculate energy transferred, charge, potential difference, power and electrical power Recall that an ammeter is connected in series Calculate the currents, potential differences and resistances in series and parallel circuits Explain how current varies with potential difference in resistors Know the functions of the wires in a plug and the safety features This lesson has been designed to fall in line with the heavy mathematical content of the Physics specification with a number of calculation tasks and students are guided through the range of skills that they will have to employ

This lesson describes the actions of the sympathetic and parasympathetic divisions of the ANS. The PowerPoint and accompanying resources are part of the 8th lesson in a series of 17 lessons that cover the details of the brain and neuropsychology topic of the AQA GCSE Psychology specification. The students were introduced to the autonomic nervous system (ANS) in the 1st lesson in this topic, so this lesson has been designed to deepen and further their understanding of the actions of this system. Students will come to understand that the sympathetic division is most active during times of stress whilst the parasympathetic division is most active during times of sleep and relaxation. Through a series of tasks including a fun quiz round, they will discover the actions of the two divisions and then be challenged to apply their understanding. This topic of the brain and neuropsychology has proved particularly difficult for the students in recent years, so I have taken time to analyse the lesson sequencing. There’s a lot of content to absorb and to understand before moving onto the next part, so I’ve tried to ensure that cross topics links and prior knowledge checks run throughout the lessons. I have organised the lessons to run through the biology content first before moving onto the psychology parts as shown by the 17 lessons below: #1 Organisation of the nervous system #2 The structure and function of the cerebral lobes #3 The cerebellum #4 The structure and function of the sensory and motor neurones #5 The relay neurones #6 Synaptic transmission #7 Excitation and inhibition at the synapse #8 The autonomic nervous system #9 The fight or flight response #10 The somatic nervous system #11 James-Lange theory of emotion #12 James-Lange theory of emotion part 2 #13 Penfield’s study of the interpretative index #14 Hebb’s theory of learning and neuronal growth #15 An introduction to neuropsychology #16 Brain scanning techniques #17 Tulving’s gold memory study

This lesson focuses on the organisation of the nervous system into the CNS and the several divisions of the PNS. The PowerPoint and accompanying resource are part of the 1st lesson in a series of 17 lessons that cover the details of the brain and neuropsychology topic of the AQA GCSE Psychology specification. This lesson has been designed to act as an introduction to the topic to allow students to understand how the brain and spinal cord (as part of the CNS) and the SNS and ANS (as part of the PNS) fit into the organisation of the system. The functions of each part are briefly introduced to give an understanding that can then be built upon in future lessons in the topic. The students will learn that the main part of the brain is the cerebrum and that this organ is divided into hemispheres. They’ll learn that the brain is connected to the other part of the CNS, the spinal cord, by the brain stem, and that these nerves are responsible for conducting impulses between the brain and the rest of the body. The differences between the somatic and autonomic nervous systems are introduced before a worksheet task challenges the students to recognise which responses are brought about by the SNS and which by the ANS. This topic of the brain and neuropsychology has proved particularly difficult for the students in recent years, so I have taken time to analyse the lesson sequencing. There’s a lot of content to absorb and to understand before moving onto the next part, so I’ve tried to ensure that cross topics links and prior knowledge checks run throughout the lessons. I have organised the lessons to run through the biology content first before moving onto the psychology parts as shown by the 17 lessons below: #1 Organisation of the nervous system #2 The structure and function of the cerebral lobes #3 The cerebellum #4 The structure and function of the sensory and motor neurones #5 The relay neurones #6 Synaptic transmission #7 Excitation and inhibition at the synapse #8 The somatic nervous system #9 The autonomic nervous system #10 The fight or flight response #11 James-Lange theory of emotion #12 James-Lange theory of emotion part 2 #13 Penfield’s study of the interpretative index #14 Hebb’s theory of learning and neuronal growth #15 An introduction to neuropsychology #16 Brain scanning techniques #17 Tulving’s gold memory study

This lesson describes the structure and localised function of the frontal, occipital, temporal and parietal lobes of the cerebrum. The PowerPoint and accompanying resources are part of the 2nd lesson in a series of 17 lessons that cover the details of the brain and neuropsychology topic of the AQA GCSE Psychology specification. In the previous lesson, the students were introduced to the cerebrum as two hemispheres connected by the corpus callosum. This lesson builds on this by introducing the cerebral cortex as the outer layer which is divided into four lobes in each hemisphere. A series of quizzes are used throughout the lesson to introduce key terms in an engaging and (hopefully) memorable way, and through one quiz, the students will discover the names of the 4 lobes and recognise where they are located. Moving forward, students will learn about the function of each lobe, including the localised function of the motor, somatosensory, visual, auditory, Broca’s and Wernicke’s areas. This topic of the brain and neuropsychology has proved particularly difficult for the students in recent years, so I have taken time to analyse the lesson sequencing. There’s a lot of content to absorb and to understand before moving onto the next part, so I’ve tried to ensure that cross topics links and prior knowledge checks run throughout the lessons. I have organised the lessons to run through the biology content first before moving onto the psychology parts as shown by the 17 lessons below: #1 Organisation of the nervous system #2 The structure and function of the cerebral lobes #3 The cerebellum #4 The structure and function of the sensory and motor neurones #5 The relay neurones #6 Synaptic transmission #7 Excitation and inhibition at the synapse #8 The somatic nervous system #9 The autonomic nervous system #10 The fight or flight response #11 James-Lange theory of emotion #12 James-Lange theory of emotion part 2 #13 Penfield’s study of the interpretative index #14 Hebb’s theory of learning and neuronal growth #15 An introduction to neuropsychology #16 Brain scanning techniques #17 Tulving’s gold memory study

This lesson describes the structure and function of the sensory and motor neurones. The PowerPoint and accompanying resources are part of the 4th lesson in a series of 17 lessons that cover the details of the brain and neuropsychology topic of the AQA GCSE Psychology specification. This lesson focuses on the functions and the structural similarities and differences between a sensory and motor neurone. Students will be introduced to key structures like the cell body, axon and dendrites and learn how they differ in these two peripheral nervous system neurones. They will also learn about the myelin sheath and will be challenged to use a data table to recognise that myelinated neurones conduct impulses faster than unmyelinated neurones. There is a brief explanation about the jumping action of the impulse between the nodes of Ranvier to enable this faster conduction. This topic of the brain and neuropsychology has proved particularly difficult for the students in recent years, so I have taken time to analyse the lesson sequencing. There’s a lot of content to absorb and to understand before moving onto the next part, so I’ve tried to ensure that cross topics links and prior knowledge checks run throughout the lessons. I have organised the lessons to run through the biology content first before moving onto the psychology parts as shown by the 17 lessons below: #1 Organisation of the nervous system #2 The structure and function of the cerebral lobes #3 The cerebellum #4 The structure and function of the sensory and motor neurones #5 The relay neurones #6 Synaptic transmission #7 Excitation and inhibition at the synapse #8 The somatic nervous system #9 The autonomic nervous system #10 The fight or flight response #11 James-Lange theory of emotion #12 James-Lange theory of emotion part 2 #13 Penfield’s study of the interpretative index #14 Hebb’s theory of learning and neuronal growth #15 An introduction to neuropsychology #16 Brain scanning techniques #17 Tulving’s gold memory study

This fully-resourced lesson describes the roles of enzymes in catalysing both intracellular and extracellular reactions and the mechanism of enzyme action. The engaging PowerPoint and accompanying resources have been designed to cover points 2.1.4 (a, b & c) of the OCR A-level Biology A specification and includes descriptions of Fischer’s lock and key hypothesis and Koshland’s induced-fit model as well as a focus on catalase and the digestive enzymes as intracellular and extracellular enzymes respectively. The lesson has been specifically planned to tie in with module 2.1.2 where protein structure and globular proteins were covered. This prior knowledge is tested through a series of exam-style questions along with current understanding and mark schemes are included in the PowerPoint so that students can assess their answers. Students will learn that enzymes are large globular proteins which contain an active site that consists of a small number of amino acids. Emil Fischer’s lock and key hypothesis is introduced to enable students to recognise that their specificity is the result of an active site that is complementary in shape to a single type of substrate. Time is taken to discuss key details such as the control of the shape of the active site by the tertiary structure of the protein. The induced-fit model is described so students can understand how the enzyme-susbtrate complex is stabilised and then students are challenged to order the sequence of events in an enzyme-controlled reaction. The final part of the lesson focuses on intracellular and extracellular enzymes. The students are challenged on their recall of the roles of DNA helicase and polymerase in DNA replication before they are challenged on their ability to apply their knowledge and understanding to an unfamiliar situation with questions about catalase and its role in the decomposition of hydrogen peroxide. The lesson concludes with one further set of exam-style questions that challenge their knowledge of carbohydrates, lipids and proteins from module 2.1.3 as they have to recognise some extracellular digestive enzymes from descriptions of their substrates.

This is a fully-resourced lesson that covers the content of specification point 5.1.5 (l) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of the sliding filament model of muscular contraction. The wide range of activities included in the lesson will engage and motivate the students whilst the understanding and previous knowledge checks will not only allow them to assess their progress but also challenge them to make links to other Biology topics. The lesson begins by using an idea from the quiz show POINTLESS to get them to recognise that myology is the study of muscles. This leads nicely into the next task, where they have to identify three further terms (from 12) which will also begin with myo and are the names of structures involved in the arrangement of skeletal muscle. Key terminology is used throughout the lesson so that students feel comfortable when they encounter this in questions. Students are introduced to the sarcomere and the bands and zones that are found within a myofibril so they can discover how most of these structures narrow but the A band, which is the length of the myosin filament, stays the same length between resting and contracted muscle. This has been designed to lead into a discussion point where they are encouraged to consider how the sarcomere can narrow but the lengths of the myofilaments can remain the same. The main task of the lesson involves the formation of a bullet point description of the sliding filament model where one event is the trigger for the next. Time is taken during this section to focus on the involvement of the calcium ions but also ATP and the idea of the sources of this molecule, including creatine phosphate, are discussed in more detail later in the lesson. The final part of the lesson involves students having to apply their knowledge by describing the effect on muscle contraction when a part of a structure is unable to function correctly. This lesson has been designed for students studying the OCR A-level Biology course and ties in nicely with the other lessons on this particular topic such as neuromuscular junctions as well as the other uploaded lessons from module 5

This is an engaging REVISION lesson which uses a range of exam questions, understanding checks, quick tasks and quiz competitions to enable students to assess their understanding of the content within topic 5 (Forces) of the AQA GCSE Physics (8463) specification. The specification points that are covered in this revision lesson include: Scalar and vector quantities Contact and non-contact forces Gravity Work done and energy transfer Forces and elasticity Moments Speed Velocity Acceleration Newton’s laws Stopping distance Momentum Conservation of momentum Changes in momentum The students will thoroughly enjoy the range of activities, which include quiz competitions such as “Fill the VOID” where they have to compete to be the 1st to complete one of the recall equations whilst all the time evaluating and assessing which areas of this topic will need their further attention. This lesson can be used as revision resource at the end of the topic or in the lead up to mocks or the actual GCSE exams

Students commonly confuse the two forms of cell division, so this revision lesson has been designed to address those mistakes and misconceptions. The PowerPoint and accompanying resources have been planned to challenge the students on their understanding of the details of points 1.2.1, 1.2.2 and 6.1.2 of the AQA GCSE biology and combined science specifications. The lesson goes through each of the three stages of the cell cycle including mitosis, to ensure that students can describe the key events and state the outcome in terms of the daughter cells. The lesson contains a series of tasks which include exam questions, discussions and a quiz which allow the students to assess their understanding. The final part of the lesson focuses on meiosis and specifically the differences to mitosis in terms of the number of cell divisions, the gametes formed, and their genetic make up. This lesson has been designed to be used for revision purposes in the lead up to the GCSE exams or in preparation for an end of topic test or mocks.

This fully-resourced revision lesson allows students to check on their understanding of Linnaeus’s and Woese’s classification systems. The engaging PowerPoint and accompanying resources have been designed to challenge the details of point B6.4 of the AQA GCSE biology and combined science specifications. The lesson contains a range of tasks including exam-questions and quizzes which provide opportunities for the students to assess their knowledge of kingdom, phylum, class, order, family, genus and species as the classification taxa and to recognise the binomial naming system. The lesson also reminds students that the three domain-system divides the Prokaryote kingdom into Archaea and Bacteria and describes how this system was developed once new evidence was discovered. As well as testing the content of B6.4, this lesson uses a series of questions to challenge understanding of linked topics which include eukaryotic and prokaryotic cell structures, microscopes, communicable diseases and ecological terms. This lesson has been planned for revision purposes in the lead up to the GCSE exams or before end of topic tests or mocks.

This lesson covers a large number of the key topics from the AQA GCSE Combined Physics course in the final weeks before the GCSE examinations. The extensive PowerPoint and accompanying resources use a range of activities and tasks including exam questions and quizzes to challenge the students on their knowledge of the following topics and skills: Units and converting between units Answering calculation questions (with 1 or 2 equations) Newton’s 2nd and 3rd laws of motion Resultant forces Conservation of energy Efficiency and reducing wasted energy Conservation of momentum Scalar and vector quantities Motions on a velocity-time graph The relationship between force and the extension of a spring Setting up electrical circuits Current, potential difference and resistance in series and parallel circuits The properties of ionising radiation Calculating half-lives Constructing decay equations The properties of waves Refraction This resource is likely to take 4 or more lessons to cover all of the content.

This engaging revision lesson uses a range of tasks to allow students to check their understanding of radioactive decay and nuclear radiation. The PowerPoint and accompanying resources have been designed to challenge the detail of point 4.2 of the AQA GCSE physics and combined science specifications and the following sub-topics are covered: Properties of alpha, beta and gamma Bq as the unit of radioactivity Detecting sources of radiation based on their penetrating power Half-life Decay equations Changes to the mass and charge of the nucleus after decay

This engaging revision lesson challenges students on their understanding of the homeostatic control system that regulates blood glucose concentration. The PowerPoint and accompanying resources have been designed to check on the understanding of the details in specification point 5.3.2 of the AQA biology and combined science specifications. A common mistake in this topic is that students confuse glycogen with glucagon and use them incorrectly so time is spent to ensure that students recognise the difference between the complex carbohydrate and the hormone. In addition to challenging the students on their knowledge of this control system, the following linked topics are also challenged: key biological terms (beginning with G) the digestive system structures in a control system

This revision lesson challenges students to explain the results of an osmosis investigation and to calculate accelerations using 2 equations. The PowerPoint and accompanying resources have been designed to check on the understanding of these two topics as detailed in the AQA GCSE biology, physics and combined specifications. The lesson contains a range of tasks including worked examples, exam questions and quizzes which will remind students that water molecules move across partially permeable membranes by osmosis and how changes in the mass of a potato can be used to compare water concentrations in the potato and solution. Students will also recall that acceleration can be calculated from velocity-time graphs using change in velocity/time as well as through the use of F=ma.

This detailed revision lesson challenges the students on their understanding of the reactions of acids with metals to produce salts and hydrogen. The PowerPoint and accompanying resources focus on the details of point 4.2.1 in the AQA GCSE chemistry and combined specifications, and time is spent reminding the students that these reactions are redox reactions. The students are given the general word equation for acids reacting with metals and are challenged to recall how to name the salts according to the metal and acid involved in the reaction. They are reminded that redox reactions involve the loss and gain of electrons and are challenged to identify the substances which are reduced or oxidised in specific examples. In addition to the reactions of acids with metals, this revision lesson also challenges them to write chemical formulae, balance symbol equations, and to identify the tests for gases.