4 Full Lesson Bundle on Amino acids, Proteins and DNA. Suitable for the AQA A Level Chemistry specification. Please review the learning objectives below.
**Lesson 1: Amino Acids **
- To know how to name and draw amino acids
- To draw the structures of amino acids as zwitterions and in acidic and alkaline solution.
- To explain how amino acids can be separated and identified by thin layer chromatography
**Lesson 2: Peptides, Polypeptides and Proteins **
- To know how to draw the structure of a peptide formed from up to three amino acids
- To identify primary, secondary and tertiary structures in diagrams
- To explain how primary, secondary and tertiary structures are maintained by hydrogen bonding and S-S bonds
Lesson 3: Hydrolysis of Peptides and Enzyme Action
- To know how to draw the structure of the amino acids formed by hydrolysis of a peptide
- To explain why a stereospecific active site can only bond to one enantiomeric form of a substrate or drug.
- To explain the principle of a drug acting as an enzyme inhibitor by blocking the active site.
Lesson 4: DNA and Anticancer Drugs
- To know how to draw the structures of the four different nucleotides that make up DNA as well as the phosphodiester bonds that connect nucleotides together to form polynucleotides
- To explain how hydrogen bonding between base pairs leads to the two complementary strands of DNA.
- To explain why cisplatin prevents DNA replication and why such drugs can have adverse effects.
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