A detailed lesson presentation (37 slides) and associated worksheets that looks at the different pieces of evidence that scientists use to support evolution and discusses how these support the theory. The lesson begins by challenging students to decide which piece of evidence is the key piece in supporting evolution (fossils). Students will then have to arrange a number of statements to describe how a fossil is formed. Students are introduced to the fossil record and questions are used to check that they understand where the oldest fossils would be found. Moving forwards, students are given three pieces of evidence that would be observed in the fossil record and they are challenged to explain how each of these supports the theory of evolution. Quick competitions are then used to get the students to see some extinct organisms in the Dodo and Woolly Mammoth and again they are questioned on how extinct animals support the theory of evolution. Further evidence in rapid changes in species and molecular comparison is discussed. There are regular progress checks throughout the lesson so that students can assess their understanding and there is a set homework included.

The AQA specification states that a minimum of 10% of the marks across the 3 assessment papers will require the use of mathematical skills. This revision lesson has been designed to include a wide range of activities that challenge the students on these exact skills because success in the maths in biology questions can prove the difference between one grade and the next! Step-by-step guides are used to walk students through the application of a number of the formulae and then exam-style questions with clear mark schemes (which are included in the PowerPoint) will allow them to assess their progress. Other activities include differentiated tasks, group discussions and quick quiz competitions such as “FROM NUMBERS 2 LETTERS” and “YOU DO THE MATH”. The lesson has been written to cover as much of the mathematical requirements section of the specification as possible but the following have been given particular attention: Hardy-Weinberg equation Chi-squared test Calculating size Converting between quantitative units Standard deviation Estimating populations of sessile and motile species Percentages and percentage change Cardiac output Geometry Due to the detail and extensiveness of this lesson, it is estimated that it will take in excess of 2/3 hours of A-level teaching time to work through the activities and it can be used throughout the duration of the course

A fully resourced lesson which includes an informative lesson presentation (34 slides) and differentiated worksheets that show students how to convert between units so they are confident to carry out these conversions when required in Science questions. The conversions which are regularly seen at GCSE are covered as well as some more obscure ones which students have to be aware of. A number of quiz competitions are used throughout the lesson to maintain motivation and to allow the students to check their progress in an engaging way This lesson has been designed for GCSE students but is suitable for KS3

This is a fully-resourced REVISION lesson that challenges the students on their knowledge of the content found in TOPIC 4 (Biodiversity and Natural resources) of the Edexcel A-level Biology (Salters Nuffield) specification. The lesson contains an engaging PowerPoint (104 slides) and accompanying worksheets that use a range of exam questions, differentiated tasks and quiz competitions to motivate the students whilst they evaluate their knowledge of the different sub-topics. The lesson has been designed to cover as much of the topic 4 specification as possible, but the following sub-topics have been given particular attention: Three-domain classification The features of the kingdoms Evolutionary relationships Behavioural, anatomical and physiological adaptations Glycosidic bonds The structure and function of cellulose The ultrastructure of plant cells Calculating the index of diversity and the heterozygosity index Applying the Hardy-Weinberg principle to calculate allele frequencies This lesson is suitable for revision at the end of the topic, in the lead up to the mocks or in the lead up to the actual A-level exams as topic 4 is assessed on both Paper 1 and Paper 2.

A concise lesson presentation (20 slides) and associated worksheet that guides students through phylogenetic trees and helps them to be able to interpret these diagrams. The lesson begins by stating three key points about the trees which will form the basis of their understanding. Moving forwards, a series of questions with explained answers are used to show how common ancestors in the past can be used to work out which present day organisms are the most closely related. Students are given lots of opportunities to assess their understanding and check that they can explain. This lesson has been written for GCSE but could be used as a recap for those students studying at A-level

This lesson describes and explains how increasing the concentration of inhibitors affects the rate of an enzyme-controlled reaction. The PowerPoint and accompanying resource are the last in a series of 5 lessons which cover the content detailed in point 1.4.2 of the AQA A-level Biology specification and describes the effect of both competitive and non-competitive inhibitors. The lesson begins with a made up round of the quiz show POINTLESS called “Biology opposites” and this will get the students to recognise that inhibition is the opposite of stimulation. This introduces inhibitors as substances that reduce the rate of a reaction and students are challenged to use their general knowledge of enzymes to identify that inhibitors prevent the formation of the enzyme-substrate complex. Moving forwards, a quick quiz competition generates the abbreviation EIC (representing enzyme-inhibitor complex) and this introduces competitive inhibitors as substances that occupy the active site. The students are asked to apply their knowledge to a new situation to work out that these inhibitors have a similar shape to the enzyme’s substrate molecule. A series of exam-style questions are used throughout the lesson and at this point, the students are challenged to work out that an increase in the substrate concentration would reduce the effect of a fixed concentration of a reversible competitive inhibitor. The rest of the lesson focuses on non-competitive inhibitors and time is taken to ensure that key details such as the disruption of the tertiary structure is understood and biological examples are used to increase the relevance. Again, students will learn that increasing the concentration of the inhibitor results in a greater inhibition and a reduced rate of reaction but that increasing the substrate concentration cannot reduce the effect as was observed with competitive inhibitors.

This lesson guides students through the use of the chi-squared test to determine the significance of the difference between observed and expected results. It is fully-resourced with a detailed PowerPoint and differentiated worksheets that have been designed to cover point 6.1.2 © of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of the test to compare the observed and expected results of a genetic cross The lesson has been written to include a step-by-step guide that demonstrates how to carry out the test in small sections. At each step, time is taken to explain any parts which could cause confusion and helpful hints are provided to increase the likelihood of success in exam questions on this topic. Students will understand how to use the phenotypic ratio to calculate the expected numbers and then how to find the critical value in order to compare it against the chi-squared value. A worked example is used to show the working which will be required to access the marks and then the main task challenges the students to apply their knowledge to a series of questions of increasing difficulty.

This extensive and fully-resourced lesson describes the principles and explains the techniques used in the production of recombinant DNA in genetic engineering. Both the engaging PowerPoint and accompanying resources have been written to cover points 6.1.3 (f) (i & ii) of the OCR A-level Biology A specification. The lesson begins with a definition of genetic engineering and recombinant DNA to allow students to begin to understand how this process involves the transfer of DNA fragments from one species to another. Links are made to the genetic code and transcription and translation mechanisms, which were met in module 2, in order to explain how the transferred gene can be translated in the transgenic organism. Moving forwards, the method involving reverse transcriptase and DNA polymerase is introduced and their knowledge of the structure of the polynucleotides and the roles of enzymes is challenged through questions and discussion points. Restriction enzymes are then introduced and time is taken to look at the structure of a restriction site as well as the production of sticky ends due to the staggered cut on the DNA. A series of exam-style questions with displayed mark schemes are used to allow the students to assess their current understanding. The second half of the lesson looks at the culture of transformed host cells as an in vivo method to amplify DNA fragments. Students will learn that bacterial cells are the most commonly transformed cells so the next task challenges their recall of the structures of these cells so that plasmid DNA can be examined from that point onwards. The following key steps are described and explained: • Remove and prepare the plasmid to act as a vector • Insert the DNA fragment into the vector • Transfer the recombinant plasmid into the host cell • Identify the cells which have taken up the recombinant plasmid • Allow the transformed host cells to replicate and express the novel gene Time is taken to explore the finer details of each step such as the addition of the promoter and terminator regions, use of the same restriction enzyme to cut the plasmid as was used to cut the gene and the different types of marker genes. As well as understanding and prior knowledge checks, quick quiz competitions are used throughout the lesson to introduce key terms such as cDNA and EcoR1 in a memorable way.

This is a fast-paced lesson which goes through the main steps of selective breeding and looks at the potential risks of this process. The lesson begins by looking at the characteristics of a number of organisms that would be selected. Time is taken to ensure that students understand that selective breeding is not a new thing and has been going on for a very long time and therefore some of the problems associated with this are now being experienced. The actual process is reduced down into 5 steps which can be recalled and applied to questions. The remainder of the lesson looks at the potential issues with selective breeding. The reduction in the nose size of pugs is explored as an example of the health problems which bred animals may face. This lesson has been written for GCSE students.

The Pearson Edexcel A-level Biology A (Salters Nuffield) specification states that a minimum of 10% of the marks across the assessment papers will require the use of mathematical skills. This revision lesson has been designed to include a wide range of activities that challenge the students on these exact skills because success in the maths in biology questions can prove the difference between one grade and the next! Step-by-step guides are used to walk students through the application of a number of the formulae and then exam-style questions with clear mark schemes (which are included in the PowerPoint) will allow them to assess their progress. Other activities include differentiated tasks, group discussions and quick quiz competitions such as “FROM NUMBERS 2 LETTERS” and “YOU DO THE MATH”. The lesson has been written to cover as much of the mathematical requirements section of the specification as possible but the following have been given particular attention: Hardy-Weinberg equation Chi-squared test Calculating size Converting between quantitative units Standard deviation Estimating populations of sessile and motile species Percentages and percentage change Cardiac output Geometry Due to the detail and extensiveness of this lesson, it is estimated that it will take in excess of 2/3 hours of A-level teaching time to work through the activities and it can be used throughout the duration of the course

This lesson describes how communication occurs between cells by cell signalling. The PowerPoint and accompanying resource have been designed to cover point 5.1.1 (b) of the OCR A-level Biology A specification and focuses on the use of the nervous system for communication between the CNS and effectors and the release of hormones to bring about responses. As this is one of the first lessons to be delivered in module 5, this lesson has been specifically planned to prepare students for the upcoming topics of neuronal and hormonal communication. Students begin by learning that cell signalling governs the basic activities of cells and coordinates multiple cell actions. Moving forwards, the next part of the lesson focuses on the nervous system and students will learn that an electrical impulse will be conducted on a somatic or an autonomic motor neurone depending upon the type of muscle to be stimulated. This provides some introductory information for modules 5.1.3 and 5.1.5. The remainder of the lesson describes how the hormones that are secreted by the cells of endocrine glands allow communication with target cells and the different actions of peptide and steroid hormones is considered.

This fully-resourced lesson describes the behaviour of chromosomes during interphase, mitosis and cytokinesis in the cell cycle. The detailed PowerPoint and accompanying resources have been designed to cover the first half of point 2.2 as detailed in the AQA A-level Biology specification whereas uncontrolled cell division and cancer and binary fission are covered in upcoming lessons. Depending upon the exam board taken at GCSE, the knowledge and understanding of mitosis and the cell cycle will differ considerably between students and there may be a number of misconceptions. This was considered at all points during the planning of the lesson and to address existing errors, key points are emphasised throughout. The cell cycle is introduced at the start of the lesson and the quantity of DNA inside the parent cell is described as diploid and as 2n. A quiz competition has been written into the lesson and this runs throughout, challenging the students to identify the quantity of DNA in the cell (in terms of n) at different points of the cycle. Moving forwards, the first real focus is interphase and the importance of DNA replication is explained so that students can initially recognise that there are pairs of identical sister chromatids and then can understand how they are separated later in the cycle. The main part of the lesson focuses on prophase, metaphase, anaphase and telophase and describes how the chromosomes behave in these stages. Centrioles were not covered in the topic 2.1 lessons on cell structures so a quick task will introduce them to these organelles who are responsible for the production of the spindle apparatus, Students will understand how the cytoplasmic division that occurs in cytokinesis results in the production of genetically identical daughter cells. This leads into a series of understanding and application questions where students have to identify the various roles of mitosis in living organisms as well as tackling a Maths in a Biology context question. The lesson concludes with a final round of MITOSIS SNAP where they only shout out this word when a match is seen between the name of a phase, an event and a picture.

An engaging lesson presentation (60 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit B2 (Organisation) of the AQA GCSE Combined Science specification (specification point 4.2) The topics that are tested within the lesson include: Principles of organisation The human digestive system The heart and blood vessels Blood Coronary heart disease The effect of lifestyle on some non-communicable diseases Plant organ systems Students will be engaged through the numerous activities including quiz rounds like “SPOT the SUBSTANCE" and “Where’s LENNY” whilst crucially being able to recognise those areas which need further attention

A series of 5 exam questions that challenge students to work out the actual size of a section as seen under a microscope or the magnification. These questions will test their ability to convert between measurements and give answers in micrometers. These questions are suitable for GCSE and A-level students

An engaging lesson presentation (16 slides) which looks at the surface area to volume ratio and ensures that students can explain why this factor is so important to the organisation of living organisms. This is a topic which is generally poorly misunderstood by students and therefore time has been taken to design an engaging lesson which highlights the key points in order to encourage greater understanding. The lesson begins by showing students the dimensions of a cube and two answers and challenges them to work out what the questions were that produced these answers. Students are shown how to calculate the surface area and the volume of an object before it is explained how this can then be turned into a ratio. Time is taken at this point to ensure that students can apply this new-found knowledge as they have to work out which of the three organisms in the “SA: V OLYMPICS” would stand aloft the podium. Students are given the opportunity to draw conclusions from this task so that they can recognise that the larger the organism, the lower the surface area to volume ratio. The lesson finishes by explaining how larger organisms, like humans, have adapted in order to increase the surface area at important exchange surfaces in their bodies. There are regular progress checks throughout the lesson to allow the students to check on their understanding. This lesson has been written for GCSE students but is perfectly suitable for A-level students who want to look at this topic from a basic level