Obviously they don´t go into as much detail as past paper questions but they do provide a basic summary of questions that students must know the answers to in each topic The answers to these sheets are also included on a separate document, so they make a great independent revision resource

This unit was planned as part of the Chemistry IB Option D - Medicinal Chemistry scheme of work, and covers all the topics at HL. It would also be suitable for other schemes of work. It includes 3 full PowerPoints, along with student versions to use as notes, which have spaces for the students to add in missing information and activities for them to complete. It also includes exam questions for practice or assessment purposes Topics covered are: Taxol - The Discovery of Paclitaxel - Isolation of Taxol - Structure of Taxol - Semi-synthetic production of Taxol - Clinical use of Taxol - The use of chiral auxiliaries to produce one enantiomer of Taxol - Confirmation of the purity of a single enantiomer drug - Thalidomide Nuclear Medicine - The use of radionuclides in medicine - Types of ionising radiation - Radiotherapy - Radioactive Decay - Targeted alpha therapy - Boron neutron capture therapy - Use of gamma emitters in radiotherapy - Radiodiagnostics - Positron Emission Tomography - Use of Technetium-99m - Half life and decay constant calculations - Magnetic Resonance Imaging Drug Detection and Analysis - Worked example of the identification of aspirin by NMR, IR and Mass Spectrometry - Worked example of the identification of an unknown compound from NMR, IR and Mass Spectrometry - Extraction and purification of organic products - Worked example of hormone concentration using partition coefficients - How polarity affects the partition coefficients - Raoult´s Law - Fractional Distillation - Drug detection in sports - Drug detection in forensic science - Chemistry of breathalyzer tests - HPLC and Gas chromatography

These 16 PowerPoints were planned as part of the IB scheme of work on Acids and Bases, Redox Chemistry and Organic Chemistry, and cover the necessary content for both the Standard and Higher Level topics. They would also be suitable for other post-16 courses. Included are fully completed PowerPoints, student versions of the PowerPoints with sections to complete independently and some exam style questions. Topics included are: - What are acids and bases? - Bronsted Lowry acids and bases (and conjugate acids and bases) - Amphiprotic and amphoteric substances - Lewis acids and bases - Reactions of acids with metals, metal oxides, metal hydroxides, metal carbonates and metal hydrogencarbonates, bases and alkalis - Making salts - What is pH and how to calculate the pH of both acids and bases - Using the dissociation constant of water to calculate pH - Acid deposition - how it occurs and how it can be treated - Calculations involving Ka, pKa, Kb, pKb, pH and pOH - Using the relationships Kw = Ka x Kb and pKa + pKb = pKw - Titration curves for titrations involving any combination of strong and weak acids and bases - Indicators - how to select a suitable indicator for a titration - How to calculate the pH of salt solutions - Buffers - what are they, how are they made and how do they work (including calculations) Reduction and Oxidation Oxidation states and how to determine them Naming compounds using oxidation states Oxidising and reducing agents Half equations in molten substances Half equations in acidic solutions The activity series Redox titrations Winkler method to determine biochemical oxygen demand Voltaic Cells Electrolytic Cells Cell potentials The standard hydrogen electrode Ecell and spontaneity Working out cell potentials Polarity and direction of electron flow The electrochemical series Electrolysis of aqueous solutions The effect of the nature of electrodes on the products Electroplating Electrolysis of water Quantitative electrolysis - Different kinds of formula e.g. molecular, empirical - Alkanes - Alkenes - Compounds involving a benzene ring - Homologous Series - IUPAC nomenclature - Naming halogenoalkanes - Naming alcohols, ethers, aldehydes, ketones and carboxylic acids - Esters - Primary, secondary and tertiary alcohols, halogenoalkanes and amines - Structural Isomerism - Functional Group Isomerism - Benzene and Aromatic Compounds - Combustion of alkanes - Reaction of alkanes with halogens - Reactions of alkenes - Addition polymerisation - Oxidation of alcohols - Nucleophilic Substitution mechanisms of primary, tertiary and secondary halogenoalkanes - Factors affecting the rate of nucleophilic substitution - Electrophilic Addition mechanisms - Markovnikov´s Rule - Electrophilic subtitution mechanisms - Reduction Reactions - Reaction pathways and synthetic routes - Cis-trans isomerism - Conformational isomerism - Optical isomerism - Optical Isomers and Plane-polarised light - Racemic mixtures - Diastereoisomers

This PowerPoint was planned as part of the IB scheme of work on Medicinal Chemistry, and covers the necessary content for the all of the Standard and Higher Level units. It would also be suitable for other post-16 courses. It includes 9 full PowerPoints, along with student versions to use as notes, which have spaces for the students to add in missing information and activities for them to complete. It also includes exam questions for practice or assessment purposes Topics covered are: Pharmaceutical Products and Drug Design - Routes of drug administration - Theraputic Effects of Drugs - The Placebo Effect - Side Effects - Calculation of the Therapeutic Index - The Therapeutic Window - Bioavailability - Tolerance and Addiction - Drug Action - Drug Development by both Drug Design and Drug Discovery Aspirin and Penicillin - History of Aspirin - Method of Producing Aspirin - Calculating the % Yield of Aspirin produced from Salicyclic Acid - Effects of Aspirin - Soluble Aspirin - Development of Penicillin - Structure of Penicllin - How Penicillin Works - Antibiotic Resistance Opiates - Morphine: Structure and action; side effects; withdrawal - How opiates cross the blood-brain barrier - Diamorphine pH regulation of the stomach - The need for stomach acid - pH calculations to determine the concentration of acid in the stomach - Antacids: equations for their reactions with stomach acid; side effects; calculation of quantity of acid neutralised - Regulation of acid production using both H2-histamine receptor blockers (Zantac) and proton pump inhibitors (Omeprazole and Esomeprazole) - Acid-base buffers: definition and calculations - Hydrogencarbonate and carbonate buffers Antivirals - The differences between viruses and bacteria - The structure of viruses - How viruses reproduce and replicate - How viruses are treated by interrupted stages of the replication process - Oseltamivir and Zanamivir - structure and action - HIV and AIDS - Treatment of HIV and AIDS Environmental impacts of Biochemistry - Effects of PACs on the environment - Antibiotic Resistance - Nuclear Waste (both LLW and HLW) - Chlorinated solvent waste - Supercritical fluid waste - Green Chemistry - Biotechnologies in Green Chemistry Taxol - The Discovery of Paclitaxel - Isolation of Taxol - Structure of Taxol - Semi-synthetic production of Taxol - Clinical use of Taxol - The use of chiral auxiliaries to produce one enantiomer of Taxol - Confirmation of the purity of a single enantiomer drug - Thalidomide Nuclear Medicine - The use of radionuclides in medicine - Types of ionising radiation - Radiotherapy - Radioactive Decay - Targeted alpha therapy - Boron neutron capture therapy - Use of gamma emitters in radiotherapy - Radiodiagnostics - Positron Emission Tomography - Use of Technetium-99m - Half life and decay constant calculations - Magnetic Resonance Imaging Drug Detection and Analysis - Worked example of the identification of aspirin by NMR, IR and Mass Spectrometry - Worked example of the identification of an unknown compound from NMR, IR and Mass Spectrometry - Extraction and purification of organic products - Worked example of hormone concentration using partition coefficients - How polarity affects the partition coefficients - Raoult´s Law - Fractional Distillation - Drug detection in sports - Drug detection in forensic science - Chemistry of breathalyzer tests - HPLC and Gas chromatography