IAL Edexcel Biology - Year 12 All lesson for cardiovascular health for unit 1 for IAL Biology (Edexcel). 1.5 (i) know how a triglyceride is synthesised by the formation of ester bonds during condensation reactions between glycerol and three fatty acids (ii) know the differences between saturated and unsaturated lipids 1.6 understand why many animals have a heart and circulation (mass transport to overcome the limitations of diffusion in meeting the requirements of organisms) 1.7 understand how the structures of blood vessels (capillaries, arteries and veins) relate to their functions 1.8 know the cardiac cycle (atrial systole, ventricular systole and cardiac diastole) and relate the structure and operation of the mammalian heart, including the major blood vessels, to its function 1.9 (i) understand the role of haemoglobin in the transport of oxygen and carbon dioxide (ii) understand the oxygen dissociation curve of haemoglobin, the Bohr effect and the significance of the oxygen affinity of fetal haemoglobin compared with adult haemoglobin 1.10 understand the course of events that leads to atherosclerosis (endothelial dysfunction, inflammatory response, plaque formation, raised blood pressure) 1.11 understand the blood clotting process (thromboplastin release, conversion of prothrombin to thrombin and fibrinogen to fibrin) and its role in cardiovascular disease (CVD) 1.12 know how factors such as genetics, diet, age, gender, high blood pressure, smoking and inactivity increase the risk of cardiovascular disease (CVD) 1.13 understand the link between dietary antioxidants and the risk of cardiovascular disease (CVD) 1.15 be able to analyse and interpret quantitative data on illness and mortality rates to determine health risks, including distinguishing between correlation and causation and recognising conflicting evidence 1.16 be able to evaluate the design of studies used to determine health risk factors, including sample selection and sample size used to collect data that is both valid and reliable 1.17 understand why people’s perception of risks are often different from the actual risks, including underestimating and overestimating the risks due to diet and other lifestyle factors in the development of heart disease 1.18 (i) be able to analyse data on the possible significance for health of blood cholesterol levels and levels of high-density lipoproteins (HDLs) and low-density lipoproteins (LDLs) (ii) know the evidence for a causal relationship between blood cholesterol levels (total cholesterol and LDL cholesterol) and cardiovascular disease (CVD) 1.19 understand how people use scientific knowledge about the effect of diet, including obesity indicators, such as body mass index and waist-to-hip ratio, exercise and smoking to reduce their risk of coronary heart disease 1.20 know the benefits and risks of treatments for cardiovascular disease (CVD) (antihypertensives, statins, anticoagulants and platelet inhibitors) Presentations for each lesson inlcuded. PEQ included in presentations with mark schemes included. Any and all feedback much appreciated

IGCSE (Edexcel) Biology 9-1 2.18 understand the process of photosynthesis and its importance in the conversion of light energy to chemical energy 2.19 know the word equation and the balanced chemical symbol equation for photosynthesis 2.20 understand how varying carbon dioxide concentration, light intensity and temperature affect the rate of photosynthesis 2.21 describe the structure of the leaf and explain how it is adapted for photosynthesis 2.22 understand that plants require mineral ions for growth, and that magnesium ions are needed for chlorophyll and nitrate ions are needed for amino acids 2.23 practical: investigate photosynthesis, showing the evolution of oxygen from a water plant, the production of starch and the requirements of light, carbon dioxide and chlorophyll 2.40B understand the role of diffusion in gas exchange 2.41B understand gas exchange (of carbon dioxide and oxygen) in relation to respiration and photosynthesis 2.42B understand how the structure of the leaf is adapted for gas exchange 2.43B describe the role of stomata in gas exchange 2.44B understand how respiration continues during the day and night, but that the net exchange of carbon dioxide and oxygen depends on the intensity of light 2.45B practical: investigate the effect of light on net gas exchange from a leaf, using hydrogen-carbonate indicator 2.53 describe the role of phloem in transporting sucrose and amino acids between the leaves and other parts of the plant 2.54 describe the role of xylem in transporting water and mineral ions from the roots to other parts of the plant 2.55B understand how water is absorbed by root hair cells 2.56B understand that transpiration is the evaporation of water from the surface of a plant 2.57B understand how the rate of transpiration is affected by changes in humidity, wind speed, temperature and light intensity 2.58B practical: investigate the role of environmental factors in determining the rate of transpiration from a leafy shoot 8x presentations, including presentations for practical lessons. Exam questions with mark schemes included throughout, with additional worksheets for lab lessons, labelling, transpiration factors, and revision (with answer sheets) Any and all feedback appreciated

IGCSE Biology 9-1 2.34 understand how the process of respiration produces ATP in living organisms 2.35 know that ATP provides energy for cells 2.36 describe the differences between aerobic and anaerobic respiration 2.37 know the word equation and the balanced chemical symbol equation for aerobic respiration in living organisms 2.38 know the word equation for anaerobic respiration in plants and in animals 2.39 practical: investigate the evolution of carbon dioxide and heat from respiring seeds or other suitable living organisms 2.46 describe the structure of the thorax, including the ribs, intercostal muscles, diaphragm, trachea, bronchi, bronchioles, alveoli and pleural membranes 2.47 understand the role of the intercostal muscles and the diaphragm in ventilation 2.48 explain how alveoli are adapted for gas exchange by diffusion between air in the lungs and blood in capillaries 2.49 understand the biological consequences of smoking in relation to the lungs and the circulatory system, including coronary heart disease 2.50 practical: investigate breathing in humans, including the release of carbon dioxide and the effect of exercise Series of lessons on respiration and gas exchange, including practical lab work and lots of practice on past paper sections on respiration and the respiratory system. Any and all feedback appreciated

IGCSE Biology 9-1 2.59 describe the composition of the blood: red blood cells, white blood cells, platelets and plasma 2.60 understand the role of plasma in the transport of carbon dioxide, digested food, urea, hormones and heat energy 2.61 understand how adaptations of red blood cells make them suitable for the transport of oxygen, including shape, the absence of a nucleus and the presence of haemoglobin 2.62 understand how the immune system responds to disease using white blood cells, illustrated by phagocytes ingesting pathogens and lymphocytes releasing antibodies specific to the pathogen 2.63B understand how vaccination results in the manufacture of memory cells, which enable future antibody production to the pathogen to occur sooner, faster and in greater quantity 2.64B understand how platelets are involved in blood clotting, which prevents blood loss and the entry of micro-organisms 2.65 describe the structure of the heart and how it functions 2.66 explain how the heart rate changes during exercise and under the influence of adrenaline 2.67 understand how factors may increase the risk of developing coronary heart disease 2.68 understand how the structure of arteries, veins and capillaries relate to their function 2.69 understand the general structure of the circulation system, including the blood vessels to and from the heart and lungs, liver and kidneys Lessons covering aspects of human transport, including blood components, adaptations of red blood cells, immune response, vaccination, cardiac structure and cycle (with heart dissection), CHD, valves, and systemic circulation. Any and all feedback appreciated

IGCSE (Edexcel) Biology 9-1 2.24 understand that a balanced diet should include appropriate proportions of carbohydrate, protein, lipid, vitamins, minerals, water and dietary fibre 2.25 identify the sources and describe the functions of carbohydrate, protein, lipid (fats and oils), vitamins A, C and D, the mineral ions calcium and iron, water and dietary fibre as components of the diet 2.26 understand how energy requirements vary with activity levels, age and pregnancy 2.27 describe the structure and function of the human alimentary canal, including the mouth, oesophagus, stomach, small intestine (duodenum and ileum), large intestine (colon and rectum) and pancreas 2.28 understand how food is moved through the gut by peristalsis 2.29 understand the role of digestive enzymes, including the digestion of starch to glucose by amylase and maltase, the digestion of proteins to amino acids by proteases and the digestion of lipids to fatty acids and glycerol by lipases 2.30 understand that bile is produced by the liver and stored in the gall bladder 2.31 understand the role of bile in neutralising stomach acid and emulsifying lipids 2.32 understand how the small intestine is adapted for absorption, including the structure of a villus 2.33B practical: investigate the energy content in a food sample 7x presentations (with worksheets, and practice exam questions where available) for the human nutrition section of the IGCSE 9-1 course. Free revision lesson as part of lesson seven. Any and all feedback is appreciated