This fully-resourced lesson describes the differences between continuous and discontinuous variation and intraspecific and interspecific variation. The engaging PowerPoint and accompanying resources have been designed to cover the first part of point 4.2.2 (f) of the OCR A-level Biology A specification but also acts as a revision tool as a number of activities challenge the students on their knowledge of the genetic code and meiosis from modules 2.1.3 and 2.1.6. The students begin the lesson by having to identify phenotype and species from their respective definitions so that a discussion can be encouraged where they will recognise that phenotypic variation between members of the same species is due to both genetic and environmental factors and that this is known as intraspecific variation. The next part of the the lesson focuses on these genetic factors, and describes how mutation and the events of meiosis contribute to this variation. A range of activities, which include exam-style questions and quick quiz rounds, are used to challenge the students on their knowledge and understanding of substitution mutations and deletions, the degenerate and non-overlapping genetic code, crossing over and independent assortment. Another quick quiz round is used to introduce polygenic inheritance and the link is made between this inheritance of genes at a number of loci as an example of continuous variation. In the following task, the students have to determine whether a statement or example represents discontinuous or continuous variation. The final part of the lesson describes a few examples where environmental factors affect phenotype, such as chlorosis in plants.

This fully-resourced lesson describes genetic biodiversity as the number of genes in a population and considers how it can be assessed. The engaging PowerPoint and accompanying differentiated resources have been primarily designed to cover point 4.2.1 (e) of the OCR A-level Biology A specification but also introduces inheritance and codominance so that students are prepared for these genetic topics when they are covered in module 6.1.2 In order to understand that 2 or more alleles can be found at a gene loci, students need to be confident with genetic terminology. Therefore the start of the lesson focuses on key terms including gene, locus, allele, recessive, genotype and phenotype. A number of these will have been met at GCSE, as well as during the earlier lessons in module 2.1.3 when considering meiosis, so a quick quiz competition is used to check on their recall of the meanings of these terms. The CFTR gene is then used as an example to demonstrate how 2 alleles results in 2 different phenotypes and therefore genetic diversity. Moving forwards, students will discover that more than 2 alleles can be found at a locus and they are challenged to work out genotypes and phenotypes for a loci with 3 alleles (shell colour in snails) and 4 alleles (coat colour in rabbits). Two calculations are provided to the students that can calculate the % of loci with more than one allele and the proportion of polymorphic gene loci. At this point, the students are introduced to codominance and again they are challenged to apply their understanding to a new situation by working out the number of phenotypes in the inheritance of blood groups. The lesson concludes with a brief consideration of the HLA gene loci, which is the most polymorphic loci in the human genome, and students are challenged to consider how this sheer number of alleles can affect the chances of tissue matches in organ transplantation

This fully-resourced lesson describes the relationship between the structure, properties and functions of triglycerides in living organisms. The engaging PowerPoint and accompanying worksheets have been designed to cover the first part of point (f) as detailed in AS unit 1, topic 1 of the WJEC A-level Biology specification and links are also made to related future topics such as the importance of the myelin sheath for the conduction of an electrical impulse which is covered in A2. The lesson begins with a focus on the basic structure and roles of lipids, including the elements that are found in this biological molecule and some of the places in living organisms where they are found. Moving forwards, the students are challenged to recall the structure of the carbohydrates from earlier in topic 1 so that the structure of a triglyceride can be introduced. Students will learn that this macromolecule is formed from one glycerol molecule and three fatty acids and have to use their understanding of condensation reactions to draw the final structure. Time is taken to look at the difference in structure and properties of saturated and unsaturated fatty acids and students will be able to identify one from the other when presented with a molecular formula. The final part of the lesson explores how the various properties of a triglyceride mean that it has numerous roles in organisms including that of an energy store and source and as an insulator of heat and electricity.

This fully-resourced lesson describes how allopatric or sympatric speciation may result from geographical, ecological or behavioural separation. The engaging PowerPoint and accompanying resources have been designed to cover point 17.3 [c] of the ICE A-level Biology specification and uses actual biological examples to increase the relevance and likelihood of understanding The lesson begins by using the example of a hinny, which is the hybrid offspring of a horse and a donkey, to challenge students to recall the biological classification of a species. Moving forwards, students are introduced to the idea of speciation and the key components of this process, such as isolation and selection pressures, are covered and discussed in detail. Understanding and prior knowledge checks are included throughout the lesson to allow the students to not only assess their progress against the current topic but also to make links to earlier topics in the specification. Time is taken to look at the details of allopatric speciation and how the different mutations that arise in the isolated populations and genetic drift will lead to genetic changes. The example of allopatric speciation in wrasse fish because of the isthmus of Panama is used to allow the students to visualise this process. The final part of the lesson considers sympatric speciation and again a wide variety of tasks are used to enable a deep understanding to be developed.

This fully-resourced lesson guides students through the construction of genetic crosses and pedigree diagrams for the inheritance of a single gene. The clear PowerPoint and accompanying resources have been designed to cover point 8.2 (ii) of the Edexcel A-level Biology B specification and includes the inheritance of multiple allele characteristics as well as those that demonstrate codominance. In order to minimise the likelihood of errors and misconceptions, step by step guides have been included throughout the lesson to support the students with the following: Writing parent genotypes Working out the different gametes that are made following meiosis Interpreting Punnett crosses to work out phenotypic ratios Students can often find pedigree trees the most difficult to interpret and to explain so exemplar answers are used as well as differentiated worksheets provided to support those students who need extra assistance.

This fully-resourced lesson describes the modes of action of the T and B lymphocytes in the immune response. The detailed PowerPoint and accompanying resources have been designed to cover point 2.4 of the CIE A-level Biology specification and the structure of antibodies and the roles of memory cells is also briefly introduced. Antigen presentation was introduced at the end of the previous lesson so the task at the start of this lesson challenges students to recognise the name of this process and then they have to spot the errors in the passage that describes the details of this event. This reminds them that contact between the APC and T lymphocytes is necessary to elicit a response which they will come to recognise as the cellular response. A series of quick quiz rounds reveals key terms in a memorable way and one that is introduced is helper T cells. Time is then taken to describe the importance of cell signalling for an effective response and students will learn how the release of chemicals by these cells activates other aspects of the response. The role of the killer T cells is also described before an exam-style question is used to check on their understanding at this point of the lesson. This leads into the section of the lesson that deals with the humoral response and students will understand how this involves the antibodies that are produced by the plasma cells that are the result of clonal selection and expansion. The remainder of the lesson focuses on the role of the antibodies and the attachment of phagocytes to opsonins.

This detailed lesson describes how the movement of water molecules by osmosis can affect both plant and animal cells. Both the PowerPoint and accompanying resources have been designed to cover specification point 2.1.5 (e) [i] as detailed in the OCR A-level Biology A specification and there is a particular focus on solutions of different water potentials. It’s likely that students will have used the term concentration in their osmosis definitions at GCSE, so the aim of the starter task is to introduce water potential to allow students to begin to recognise osmosis as the movement of water molecules from a high water potential to a lower potential, with the water potential gradient. Time is taken to describe the finer details of water potential to enable students to understand that 0 is the highest value (pure water) and that this becomes negative once solutes are dissolved. Exam-style questions are used throughout the lesson to check on current understanding as well as prior knowledge checks which make links to previously covered topics such as the lipid bilayer of the cell membrane. The remainder of the lesson focuses on the movement of water when animal and plant cells are suspended in hypotonic, hypertonic or isotonic solutions and the final appearance of these cells is described, including any issues this may cause. This lesson has been specifically written to tie in with the previous two lessons covering 2.1.5 (b) & (d) where the cell membrane, diffusion and active transport were described.

A concise lesson presentation that focuses on the key details that students need to know about diodes for the GCSE examinations. The lesson begins by introducing the idea that diodes only allow current to flow in one direction. Moving forwards, time is taken to go through the potential difference vs current graph in 3 parts so that students can explain how the diode functions. Moving forwards, students will meet a LED and then in the style commonly associated with the 6 mark exam question, they are challenged to use data in a table to compare the effectiveness of a LED against other light bulbs.

A concise lesson presentation (26 slides) that looks at how sexual reproduction leads to variation and considers the advantages and disadvantages of this form of reproduction. The lesson begins by getting the students to recognise that sexual reproduction needs two parents and therefore two gametes. Time is taken to ensure that students understand that these gametes are produced by meiosis and therefore contain the haploid number of chromosomes. Key terminology like haploid and zygote are used throughout the lesson. This lesson is suitable for both KS3 and GCSE students

This lesson describes how the structure of the mammalian lung is adapted for rapid gaseous exchange. The engaging PowerPoint has been designed to cover point 2.1 (iii) of the Edexcel International A-level Biology specification and focuses on the essential features of the alveolar epithelium as well as the mechanism of ventilation to maintain a steep concentration gradient for the simple diffusion of oxygen and carbon dioxide. Gas exchange at the alveoli is a topic that was covered at GCSE and considered during the previous lessons in topic 2.1 so this lesson has been written to challenge the recall of that knowledge and to build on it. The main focus of the first half of the lesson is the type of epithelium found lining the alveoli and students will discover that a single layer of flattened cells known as simple, squamous epithelium acts to reduce the diffusion distance. The following features of the alveolar epithelium are also covered: Surface area Moist lining Production of surfactant The maintenance of a steep concentration gradient is the role of the respiratory system and the next part of the lesson focuses on the diaphragm and intercostal muscles. As the mechanism of inhalation is a cascade of events, the details of this process are covered in a step by step format using bullet points. At each step, time is taken to discuss the key details which includes an introduction to Boyle’s law that reveals the inverse relationship between volume and pressure. It is crucial that students are able to describe how the actions of the diaphragm, external intercostal muscles and ribcage result in an increased volume of the thoracic cavity and a subsequent decrease in the pressure, which is below the pressure outside of the body. At this point, their recall of the structures of the mammalian gas exchange system is tested, to ensure that they can describe the pathway the air takes on moving into the lungs.

This engaging lesson looks at the role of haemoglobin in carrying oxygen and carbon dioxide. The PowerPoint has been designed to cover point 8.1 (f) of the CIE International A-level Biology specification and includes references to the role of carbonic anhydrase and the formation of haemoglobinic acid and carbaminohaemoglobin. The lesson begins with a version of the quiz show Pointless to introduce haemotology as the study of the blood conditions. Students are told that haemoglobin has a quaternary structure and are challenged to use their prior knowledge of biological molecules to determine what this means for the protein. They will learn that each of the 4 polypeptide chains contains a haem group with an iron ion attached and that it is this group which has a high affinity for oxygen. Time is taken to discuss how this protein must be able to load (and unload) oxygen as well as transport the molecules to the respiring tissues. Students will plot the oxyhaemoglobin dissociation curve and the S-shaped curve is used to encourage discussions about the ease with which haemoglobin loads each molecule. The remainder of the lesson looks at the different ways that carbon dioxide is transported around the body that involve haemoglobin. Time is taken to look at the dissociation of carbonic acid into hydrogen ions so that students can understand how this will affect the affinity of haemoglobin for oxygen in an upcoming lesson on the Bohr effect.

A fun and engaging lesson presentation (74 slides) and accompanying differentiated worksheets that uses exam questions with displayed mark schemes and competitions to enable students to assess their understanding of Module C4 (Predicting and identifying reactions and products). The following topics within the combined Science specification are covered by the tasks: C4.1 Predicting chemical reactions Group 1 - the alkali metals Group 7 - the halogens Halogen displacement reactions Group 0 - the noble gases Reactivity of elements C4.2 Identifying the products of chemical reactions Detecting gases Students will be able to use the understanding checks to see which areas of the specification need more attention

This engaging and detailed lesson presentation (43 slides) uses a step by step guide to take students through the important scientific skill of drawing graphs to represent data and address all the misconceptions and misunderstandings that often accompany this topic. The lesson begins by explaining to the students how to decide whether data should be represented on a line graph or a bar chart and a competition called "To BAR or not to BAR" is used to allow them to check their understanding while maintaining motivation. Moving forwards, students are shown a 6 step guide to drawing a line graph. Included along the way are graphs that are wrong and explanations as to why so that students can see what to avoid. There are continuous progress checks and a homework is also included as part of the lesson. This lesson is written for students of all ages who are studying Science.

This fully-resourced lesson looks at the process and site of the Krebs cycle and explains the importance of decarboxylation, dehydrogenation, the reduction of NAD and FAD and substrate level phosphorylation. The engaging and detailed PowerPoint and accompanying resource have both been designed to cover point 5.2.2 (e) of the OCR A-level Biology A specification and includes the formation of citrate from the acetyl group of acetyl CoA and oxaloacetate and the regeneration of this four carbon molecule. The lesson begins with a version of the Impossible game where students have to spot the connection between 8 of the 9 terms and will ultimately learn that this next stage is called the Krebs cycle. The main part of the lesson challenges the students to use descriptions of the main steps of the cycle to continue their diagram of the oxidation-reduction reactions. Students are continually exposed to key terminology such as decarboxylation and dehydrogenation and they will learn where carbon dioxide is lost and reduced NAD and FAD are generated. They will also recognise that ATP is synthesised by substrate level phosphorylation. The final task challenges them to apply their knowledge of the cycle to work out the numbers of the different products and to calculate the number of ATP that must be produced in the next stage if the theoretical yield of 32ATP is to be achieved. This lesson has been designed to tie in with the other uploaded lessons on glycolysis, anaerobic respiration, the Link reaction, oxidative phosphorylation and respiratory substrates

This fully-resourced lesson looks at the process and site of glycolysis and explains how the phosphorylation of glucose and the production and oxidation of triose phosphate results in 2 molecules of pyruvate. The engaging PowerPoint and accompanying differentiated resources have been designed to cover point 5.2.2 © of the OCR A-level Biology A specification. The lesson begins with the introduction of the name of the stage and then explains how the phosphorylation, splitting and oxidation are the three main stages that need to be known for this specification. Time is taken to explain the key details of each of these stages and key points such as the use of ATP in phosphorylation are explained so that students can understand how this affects the net yield. A quick quiz competition is used to introduce NAD and the students will learn that the reduction of this coenzyme, which is followed by the transport of the protons and electrons to the cristae for the electron transport chain, is critical for the overall production of ATP. Understanding checks, in a range of forms, are included throughout the lesson so that students can assess their progress and any misconceptions are immediately addressed. This lesson has been written to tie in with the other uploaded lessons on the Link reaction, Krebs cycle, oxidative phosphorylation and anaerobic respiration

An engaging lesson presentation (43 slides) that uses exam questions, quick tasks and competitions to enable students to assess their understanding of the topics within module 6.1.3 of the OCR A-Level Biology A specification. All of the exam questions have displayed mark schemes and explanations so that students can recognise any errors or misconceptions. Competition rounds included in this lesson are "From numbers 2 letters" and "Is this SEQUENCED correctly".

An engaging lesson presentation (78 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within module P4 (Waves and radioactivity) of the OCR Gateway A GCSE Combined Science specification. The topics that are tested within the lesson include: Waves and their properties Wave velocity Electromagnetic waves Atoms and isotopes Alpha, beta, gamma Nuclear equations Half-life Radiation and the human body Students will be engaged through the numerous activities including quiz rounds like “Tell EM the Word” and “Take the HOTSEAT” whilst crucially being able to recognise those areas which need further attention

An engaging lesson presentation (64 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within TOPIC 8 (Chemical analysis) of the AQA GCSE Chemistry specification (specification point C4.8) The topics that are tested within the lesson include: Pure substances Chromatography Identification of common gases Identification of ions Students will be engaged through the numerous activities including quiz rounds like “Take the CHROMATOGRAPHY hotseat” whilst crucially being able to recognise those areas which need further attention